Download Advances in Polyurethane Biomaterials by Stuart L. Cooper, Jianjun Guan PDF

By Stuart L. Cooper, Jianjun Guan

Advances in Polyurethane Biomaterials brings jointly a radical evaluation of advances within the homes and purposes of polyurethanes for biomedical functions. the 1st set of chapters within the ebook presents an enormous assessment of the basics of this fabric with chapters on homes and processing tools for polyurethane. extra sections disguise major makes use of comparable to their tissue engineering and vascular and drug supply applications

Written by way of a global staff of prime authors, the ebook is a entire and crucial reference in this very important biomaterial.

  • Brings jointly in-depth insurance of a huge fabric, crucial for lots of complex biomedical applications
  • Connects the basics of polyurethanes with state of the art research of important new functions, together with tissue engineering and drug delivery
  • Written through a workforce of hugely a professional authors with more than a few expert and educational event, overseen through an editor who's a number one professional within the field

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Advances in Polyurethane Biomaterials

Advances in Polyurethane Biomaterials brings jointly an intensive evaluate of advances within the homes and functions of polyurethanes for biomedical purposes. the 1st set of chapters within the ebook presents a massive evaluation of the basics of this fabric with chapters on homes and processing tools for polyurethane.

Additional resources for Advances in Polyurethane Biomaterials

Sample text

To achieve this goal, PU–FPC is synthesized by putting fluorocarbon and phosphorous choline groups together because fluorine has a much lower surface energy and has a great tendency to concentrate at Surface characterization techniques 33 the polymer/air interface. 2). 2). Polyethylene glycol (PEG) is another well-known molecule used to reduce protein adsorption and/or platelet adhesion. Surface enrichment of a triblock oligomeric PEG containing additive from a polyurethane matrix was reported [54,55].

Biodegradable poly(ethylene oxide)/poly(e-caprolactone) multiblock copolymers. J Biomed Mater Res 2002;59(2):273–81. [47] Benhardt H, et al. Synthesis of collagenase‐sensitive polyureas for ligament tissue engineering. Macromol Biosci 2011;11(8):1020–30. [48] Guan J, Wagner WR. Synthesis, characterization and cytocompatibility of polyurethaneurea elastomers with designed elastase sensitivity. Biomacromolecules 2005;6(5): 2833–42. [49] Abraham G, Marcos-Fernandez A, San Roman J. Bioresorbable poly(ester-ether urethane)s from l-lysine diisocyanate and triblock copolymers with different hydrophilic character.

Thus the surface properties of polyurethane biomaterials are the key factors in determining the performance of finished products. Deficiencies in surface properties are the leading cause of implant failure such as surface e­ rosion, immune response, chronic inflammation, thrombi formation, and bacterial infection. For this reason, a tremendous amount of research has been focused on surface ­modification of polyurethane biomaterials to improve their lubricity, hydrophilicity/­ hydrophobicity, hemocompatability, antithromobogenicity, and antimicrobial activity.

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